Related Experiment Video
Updated: Jun 17, 2026
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
[Changes in visual evoked potentials curve parameters in children with amblyopia]
Dobrila Karlica1, Davor Galetović, Kajo Bućan
1University Department of Ophthalmology, Split University Hospital Center, Split, Croatia. ocna.klinika@kbsplit.hr
Insights
Visual evoked potential (VEP) parameters correlate with visual acuity in amblyopic children. Improved visual acuity showed higher VEP amplitude and shorter latency, suggesting VEP
Area of Science:
- Ophthalmology and Visual Neuroscience
- Pediatric Optometry
- Neurophysiology
Context:
- Amblyopia, often termed 'lazy eye,' affects visual development in children.
- Assessing visual acuity in young children can be challenging.
- Visual evoked potential (VEP) measures the brain's electrical response to visual stimuli.
Purpose:
- To investigate the correlation between visual evoked potential (VEP) parameters (amplitude and latency) and visual acuity in children with anisometropic amblyopia.
- To evaluate VEP changes in response to refractive correction and pleoptic therapy.
Summary:
- VEP parameters, including P100 wave amplitude and latency, were recorded in 30 children (4.5-6 years) before and after refractive correction and pleoptic therapy.
- A statistically significant correlation was found between VEP amplitude and latency with visual acuity (P<0.001).
- VEP values demonstrated significant differences across treatment stages, with improved visual acuity associated with higher amplitude and shorter latency.
Impact:
- VEP assessment may serve as a valuable, objective tool for determining amblyopia severity and monitoring treatment efficacy in children.
- Findings support the use of VEP in clinical practice for managing amblyopic patients.
- This study contributes to understanding the neurophysiological basis of visual development in amblyopia.
Aim:
The aim of the study was to correlate visual evoked potential (VEP) parameters (amplitude and latency) with visual acuity of the amblyopic eye.
Patients And Methods:
The study included 30 children aged 4.5-6 years, tested for visual acuity before refractive correction, with correction, and after pleoptic therapy. In addition, VEP parameters were recorded according to changes in visual acuity.
Results:
VEP curves were found to change with visual acuity of the amblyopic eye. A statistically significant correlation was obtained between amplitude values and visual acuity as well as between latency values and visual acuity (P<0.001 both).
Discussion:
Some authors have reported differences in VEP curve parameters according to visual acuity. We performed VEP assessment in children with anisometropic amblyopia and found statistically significant differences among the values obtained before refractive correction, with refractive correction and after pleoptic treatment of amblyopic eye. VEP curve values changed with improvement in visual acuity: the P100 wave amplitude was higher and latency shorter.
Conclusion:
VEP may be a valid method to determine amblyopia.
