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Updated: Jun 17, 2026

Quantifying the Binding Interactions Between Cu(II) and Peptide Residues in the Presence and Absence of Chromophores
Published on: April 5, 2022
Spectroscopic characterization of Cu(II) complex of L-phenylalanine and D,L-tryptophan
1Department of Chemistry, Faculty of Sciences and Letters, Trakya University, 22030 Edirne, Turkey. ozlenaltun@yahoo.com
Abstract:
In this work, the reactions involving L-phenylalanine and D,L-tryptophan in the presence of Cu(II) ion were studied. Optimum conditions for the reactions were established as pH 7 and lambda=641 nm. When the reaction was kinetic, it was observed that the following rate formula was found as dA/A(n)=k dt and k=3.2 x 10(-4)s(-1), according to absorbance measurements. Using a perpetual change curve, the ratio of [Cu]/[Cu]+L-phenylalanine+[D,L-tryptophan] was found 1:1:1. According to this result, one molecule of L-phenylalanine and one molecule of D,L-tryptophan react with one molecule Cu(II) ion.
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