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Updated: Jun 17, 2026
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Published on: July 20, 2014
Primary yolk sac tumor of the urachus
Alfredo Ernesto Romero-Rojas1, Oscar Alberto Messa-Botero, Mario Alexander Melo-Uribe
1Grupo de Patología del Instituto Nacional de Cancerología INC, Bogotá, Colombia. aromero@cancer.gov.co
Introduction:
Neoplasms originating from the urachus are rare. The most common urachal malignancy is adenocarcinoma, whereas extragonadal germ cell tumors, primarily of the urachus, are an extremely rare finding.
Objective:
To describe a primary yolk sac tumor (YST) of the urachus in an adult.
Case Report:
A 44-year-old woman presented with 6 months of pelvic pain associated with a sensation of progressive mass growth. At the time of tumor resection, the tumor was found to be attached by a pedicle to the dome of the bladder, with no injury to the adjacent organs. Pathological study showed a neoplasm with epithelioid cells, pseudocysts, a myxomatous background, and Schiller-Duval body formations. Immunohistochemistry stains showed positivity to AE1/AE3, α-1-fetoprotein, and α-1-antitrypsin and negativity to other markers.
Conclusion:
An unusual case of a YST in the urachus is presented. This is the first reported adult case based on the authors' bibliographic search.
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