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Updated: Jun 17, 2026
06:34
Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS
Published on: July 11, 2016
Direct 16S rRNA gene sequencing of polymicrobial culture-negative samples with analysis of mixed chromatograms
Gitte N Hartmeyer1, Ulrik S Justesen1
1Department of Clinical Microbiology, Odense University Hospital, Odense,Denmark.
Journal of Medical Microbiology
|December 26, 2009
Abstract:
Two cases involving polymicrobial culture-negative samples were investigated by 16S rRNA gene sequencing, with analysis of mixed chromatograms. Fusobacterium necrophorum, Prevotella intermedia and Streptococcus constellatus were identified from pleural fluid in a patient with Lemierre's syndrome and Neisseria meningitidis and Escherichia coli were identified from a petechia in a patient with meningococcal disease.
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