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Related Experiment Video

Updated: Jun 17, 2026

Partial Optic Nerve Transection in Rats: A Model Established with a New Operative Approach to Assess Secondary Degeneration of Retinal Ganglion Cells

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Nonaccidental trauma and peripheral retinal nonperfusion.

David T Goldenberg¹, Deborah Wu, Antonio Capone

¹Associated Retinal Consultants, Royal Oak, Michigan, USA. davidtgold@yahoo.com

|December 29, 2009

Summary

Fluorescein angiography revealed peripheral retinal nonperfusion in infants with nonaccidental trauma (NAT). Hemorrhage associated with NAT may indicate retinal nonperfusion, warranting physician consideration of FA.

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System for Focal, Closed-System Central Nervous System Injury

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System for Focal, Closed-System Central Nervous System Injury

System for Focal, Closed-System Central Nervous System Injury

Published on: November 29, 2024

Area of Science:

Ophthalmology
Pediatric Medicine
Medical Imaging

Background:

Nonaccidental trauma (NAT) can cause severe ocular injuries in children.
Retinal vascular alterations are a key finding in these cases.
Fluorescein angiography (FA) is crucial for diagnosing vascular changes.

Observation:

A retrospective study reviewed 10 eyes of 5 children diagnosed with NAT.
Ophthalmic evaluations included fundus photography and FA.
The study focused on identifying retinal vascular perfusion, neovascularization, and detachment.

Findings:

Seven of 10 eyes showed peripheral retinal nonperfusion on FA.
Nonperfusion involved both arterial and venous sides of the retinal vascular tree.
Retinal nonperfusion was consistently associated with preretinal or vitreous hemorrhage.

Implications:

FA can detect significant retinal vascular alterations in children with suspected NAT.
Preretinal/vitreous hemorrhage may signal underlying retinal nonperfusion.
Physicians should consider FA in evaluating NAT, with close monitoring for neovascularization.