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Updated: Jun 17, 2026

Reliability of Artificial Intelligence-Based Cone Beam Computed Tomography Integration with Digital Dental Images
Published on: February 23, 2024
Reproducibility of 3 different tracing methods based on cone beam computed tomography in determining the anatomical
Niek L Gerlach1, Gert J Meijer, Thomas J J Maal
1Department of Oral and Maxillofacial Surgery, Radboud University Nijmegen, Medical Centre, Nijmegen, The Netherlands.
Purpose:
To investigate the reproducibility of 3 different tracing methods to determine a reliable method to define the proper anatomical position of the mandibular canal based on cone beam computed tomography (CBCT) data.
Materials And Methods:
Five dentate and 5 edentate patients were selected at random from the CBCT database. Two independent observers traced both the left and the right mandibular canal using 3-dimensional image-based planning software (Procera System NobelGuide; Nobel Biocare, Göteborg, Sweden). All mandibular canals were traced using 3 different methods. Method I was based on coronal views, also known as cross-sections. Panorama-like reconstructions were the starting point for method II. The third method combined methods I and II.
Results:
With respect to interobserver reliability, no significant difference (P = .34) for the various methods was observed. The reproducibility was better in edentate than in dentate jaws (P = .0015). The difference between 2 tracings was the lowest for the combined method: within a range of 1.3 mm in 95% of the course of the canal. The most obvious deviations were mainly seen in the anterior part of the canal.
Conclusions:
The best reproducible method for mandibular canal tracing is the combined method III. Between observers, still a mean 95th percentile deviation threshold of 1.3 mm (SD 0.384) is noted, indicating that a safety zone of 1.7 mm should be respected. When planning surgery on CBCT-based data, surgeons should be aware of the obvious deviations located in the region of the anterior loop of the canal.

