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Related Concept Videos

Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
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Allergies and anaphylaxis:...
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Prevention of Further Absorption of Poison01:14

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In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...

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Updated: Jun 17, 2026

Measuring Local Anaphylaxis in Mice
07:49

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Published on: October 14, 2014

Management protocol for anaphylaxis.

Rohit Sharma1, Ramen Sinha, P S Menon

  • 1Military Dental Center, Jalandhar, India.

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
|December 29, 2009
PubMed
Summary
This summary is machine-generated.

Anaphylaxis lacks a universal definition and diagnostic criteria despite being known for over a century. Ongoing efforts aim to establish consensus on its definition, diagnosis, and management.

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Last Updated: Jun 17, 2026

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Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
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Published on: September 14, 2018

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Area of Science:

  • Emergency Medicine
  • Allergy and Immunology

Background:

  • Anaphylaxis has been recognized in emergency medicine for over 100 years.
  • A universal definition and diagnostic criteria for anaphylaxis are currently lacking.
  • International consensus is needed for consistent diagnosis and management.

Purpose of the Study:

  • To present the latest concepts on anaphylaxis from current literature.
  • To highlight research needs in the field of anaphylaxis.
  • To contribute to the ongoing efforts for a universally accepted definition and diagnostic criteria.

Main Methods:

  • Review of current literature on anaphylaxis.
  • Summary of findings from expert meetings convened by NIAID and FAAN.
  • Synthesis of concepts and identification of research gaps.

Main Results:

  • The article synthesizes recent literature and expert discussions on anaphylaxis.
  • It identifies areas requiring further research to improve understanding and care.
  • Progress is being made towards a consensus definition and diagnostic criteria.

Conclusions:

  • Establishing a universally accepted definition and diagnostic criteria for anaphylaxis remains a priority.
  • Further research is crucial to refine diagnostic approaches and management strategies.
  • Collaborative efforts are essential to advance the field of anaphylaxis.