Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Malignant primitive neuroectodermal tumor presenting as a scalp nodule.

C M Jacinto1, J M Grant-Kels, D R Knibbs

  • 1Department of Medicine, Hartford Hospital, Connecticut.

The American Journal of Dermatopathology
|February 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lost in translation: true clinical impact of reflectance confocal microscopy overlooked in 'Biopsy outperforms reflectance confocal microscopy in diagnosing and subtyping basal cell carcinoma: results and experiences from a randomized controlled multicentre trial'.

The British journal of dermatology·2020
Same author

Cell phone use in the clinic: "Please hang up now, the doctor is ready to see you!"

International journal of women's dermatology·2019
Same author

A deep look into thin melanomas: What's new for the clinician and the impact on the patient.

International journal of women's dermatology·2018
Same author

Skin cancer knowledge, attitudes, beliefs, and prevention practices among medical students: A systematic search and literature review.

International journal of women's dermatology·2018
Same author

A survey assessing the satisfaction of dermatology residents in the United States: How can we make dermatology residency training better?

International journal of women's dermatology·2018
Same author

Applying to dermatology residency: An ethical approach to an inherently unethical process.

International journal of women's dermatology·2018
Same journal

Myxoid Variant of Primary Cutaneous Anaplastic Large Cell Lymphoma Mimicking Soft Tissue Sarcoma: Diagnostic Pitfalls and Literature Review.

The American Journal of dermatopathology·2026
Same journal

Herpetic Whitlow in Association With a Cutaneous Infiltrate of Chronic Lymphocytic Leukemia.

The American Journal of dermatopathology·2026
Same journal

Basal Cell Carcinosarcoma with an Osteosarcomatous Component: A Case Report Supporting the Diagnostic Utility of SATB2 and TRAP Immunostaining with a Literature Review of 22 Cases.

The American Journal of dermatopathology·2026
Same journal

Demonstration of 23-Gene Expression Profile Test Utility Within PRAME Immunohistochemistry Results: A Case Series.

The American Journal of dermatopathology·2026
Same journal

On the Progression From Early-to Late-Stage Melanoma: A Potential Sequence of Molecular Events Using Data From Droplet Digital PCR and Array Comparative Genomic Hybridization, A Pilot Study.

The American Journal of dermatopathology·2026
Same journal

Montgomery Tubercles in the Male Areola: Histological Observations and a Brief About Past Investigators.

The American Journal of dermatopathology·2026
See all related articles

A rare malignant epithelioid schwannoma mimicked a benign scalp lesion in a young woman. Diagnosis required advanced techniques like immunohistochemistry and ultrastructural examination for this undifferentiated neoplasm.

Area of Science:

  • Dermatopathology
  • Oncology
  • Surgical Pathology

Background:

  • Malignant epithelioid schwannoma is a rare soft tissue tumor.
  • Superficial tissue presentation is uncommon, often leading to diagnostic challenges.

Observation:

  • A 20-year-old woman presented with a 3-year history of a stable, benign-appearing cystic nodule on her scalp.
  • Excision revealed a malignant small round cell undifferentiated neoplasm.

Findings:

  • Immunohistochemistry suggested neural crest origin.
  • Ultrastructural examination confirmed schwannian differentiation.
  • Diagnosis was established as malignant epithelioid schwannoma of superficial tissue, also known as neurotropic or desmoplastic melanoma.

Implications:

Related Experiment Videos

  • This case highlights the diagnostic difficulties associated with rare malignant tumors presenting as seemingly benign lesions.
  • Specialized techniques are crucial for accurate diagnosis and appropriate patient management.
  • Understanding the immunohistochemical and ultrastructural features aids in differentiating this neoplasm from other small round cell tumors.