In vitro evaluation of MR imaging issues at 3T for aneurysm clips made from MP35N: Findings and information applied

F G Shellock1, S Valencerina

  • 1University of Southern California and Institute for Magnetic Resonance Safety, Education, and Research, Los Angeles, 90045, USA. frank.shellock@gte.net

Abstract

Insights

This study found that specific MP35N aneurysm clips are safe for 3T MRI scans, showing minimal magnetic interactions and heating. Artifacts were noted but deemed manageable for safe magnetic resonance imaging (MRI).

Area of Science:

  • Biomaterials Science
  • Medical Imaging Physics
  • Neurosurgery Devices

Background:

  • Aneurysm clips require rigorous safety evaluation for Magnetic Resonance Imaging (MRI) at 3 Tesla (3T).
  • Key concerns include magnetic field interactions, radiofrequency (RF) induced heating, and image artifact generation.
  • MP35N alloy is a common material for neurovascular clips.

Purpose of the Study:

  • To assess the safety of specific MP35N aneurysm clips for 3T MRI.
  • To characterize potential risks such as magnetic field interactions, heating, and image artifacts.
  • To determine if these clips meet the criteria for "MR conditional" labeling.

Main Methods:

  • Three distinct MP35N aneurysm clips were tested at 3T.
  • Magnetic field interactions were evaluated.
  • RF-induced heating was measured in a gelled-saline phantom at a specific absorption rate (SAR) of 3 W/kg.
  • Image artifacts were characterized using T1-SE and GRE sequences.

Main Results:

  • Aneurysm clips exhibited minor magnetic field interactions, insufficient to cause in situ movement.
  • RF-induced heating was minimal, with the highest temperature increase below 1.8°C.
  • Image artifacts were observed, potentially impacting visualization near the clip.

Conclusions:

  • The tested MP35N aneurysm clips are considered "MR conditional" for patients undergoing 3T MRI.
  • These findings are applicable to 155 additional aneurysm clips made from the same MP35N material.
  • The study supports the safe use of these devices in a 3T MRI environment with artifact awareness.