[A case of advanced esophageal cancer that has come back eight years after combined modality therapy]

The case is for a woman of 77 years old. In February 1992, right thoracotomy subtotal thoracic esophagectomy was performed after performing preoperative chemotherapy (FP therapy) for advanced esophageal cancer for two courses. The pathological diagnosis was Mt, mod. diff. sqcc, mp, n4 (#2: 1/13, #9: 3/4), ly2, v0, stage IVa. As a postoperative adjuvant therapy, FP therapy was performed for two courses and we took a wait-and-see approach as an outpatient since then. As we found lymph node metastasis surrounding the root of celiac artery and right renal vein by an abdominal CT in October 1999, nedaplatin+5-FU therapy was performed for 5 courses/24 weeks as second-line chemotherapy, and furthermore, a radiation therapy, linac 50 Gy was performed. The involved lymph node was reduced and the therapy evaluation was CR. After that, a home-healthcare period of about six months was obtained. We have experienced a case of advanced esophageal cancer that has come back eight years after combined modality therapy, and after that, the patient could obtain a long-term survival with a marked effect of chemotherapy.