Related Experiment Video
Updated: Jun 17, 2026
09:29
An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing
Published on: May 13, 2020
Is tin fume exposure benign or not? Two case reports
Ayşe Yilmaz1, Serpil Göçmen Ocal, Sibel Doruk
1Department of Chest Disease, Faculty of Medicine, Gaziosmanpaşa University, Tokat, Turkey. ayse1106@mynet.com
Tuberkuloz Ve Toraks
|December 29, 2009
Summary
Stannosis, a lung disease from tin oxide dust, shows dense nodules on X-rays but usually mild symptoms. However, two cases revealed severe respiratory failure despite initial mild presentation.
Area of Science:
- Occupational Medicine
- Pulmonary Pathology
- Radiology
Background:
- Stannosis is a non-fibrotic pneumoconiosis caused by inhaling tin oxide dust.
- It is characterized by dense nodular opacities on chest radiographs.
Observation:
- Two cases of stannosis are presented, involving a 70-year-old male tinner and a 50-year-old female exposed to tin fume.
- Radiological findings included diffuse reticulonodular opacities, dense nodules, reticulation, and honeycomb appearance on HRCT.
- Pulmonary function tests (PFTs) initially showed minimal impairment.
Findings:
- Despite radiological evidence and initial PFTs suggesting mild disease, both patients experienced clinical deterioration.
- Both patients ultimately died from respiratory failure, contrary to the typically benign clinical course of stannosis.
Implications:
- This highlights a potentially severe, under-recognized clinical trajectory of stannosis.
- Further research is needed to understand the factors contributing to severe outcomes in stannosis.
- Occupational exposure to tin oxide requires careful monitoring and management.
Related Concept Videos
01:31Pulmonary Tuberculosis III
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
01:29Pulmonary Tuberculosis I
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
01:36Types of Toxins
Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
01:28Pulmonary Tuberculosis II
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...