Related Experiment Video
Updated: Jun 17, 2026
10:24
Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
Published on: February 12, 2018
Sutureless human sclera donor patch graft for Ahmed glaucoma valve
Lucio Zeppa1, Mario R Romano, Luigi Capasso
1Unità Operativa di Oculistica, Presidio Ospedaliero Giuseppe Moscati, Avellino - Italy.
European Journal of Ophthalmology
|December 29, 2009
Summary
Sutureless human sclera donor patch grafts effectively prevent erosion of glaucoma drainage implant tubes. This safe procedure lowers intraocular pressure in complicated glaucoma cases.
Area of Science:
- Ophthalmology
- Glaucoma Surgery
- Ocular Surface Reconstruction
Background:
- Glaucoma drainage implants are crucial for managing refractory glaucoma.
- Conjunctival erosion over implant tubes is a significant complication, potentially leading to vision loss.
- Sutureless patch grafts offer a novel approach to mitigate this risk.
Purpose of the Study:
- To evaluate the safety and effectiveness of sutureless human sclera donor patch grafts.
- To assess the prevention of conjunctival erosion over glaucoma drainage implant tubes.
- To determine the impact on intraocular pressure and visual acuity.
Main Methods:
- Prospective pilot study involving 15 patients with refractory glaucoma.
- Ahmed glaucoma valve (AGV) implantation with a sutureless human sclera donor patch graft.
- Scleral graft secured with fibrin glue, followed by 12-month monitoring.
Main Results:
- Significant reduction in mean intraocular pressure from 29.8 to postoperative levels.
- No conjunctival erosion or endophthalmitis observed in any patient.
- Scleral patch remained in place throughout the 12-month follow-up period.
Conclusions:
- Sutureless human sclera donor patch grafts are effective and safe for AGV implants.
- This technique successfully prevents conjunctival erosion over the implant tube.
- The procedure is a viable option for complicated glaucoma management.
