Related Experiment Video
Updated: Jun 17, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
[Congenital epidermolysis bullosa: a review]
C Siañez-González1, R Pezoa-Jares, J C Salas-Alanis
1Escuela de Medicina del Instituto Tecnológico y de Estudios Superiores de Monterrey, Nuevo León, México.
Abstract:
Epidermolysis bullosa is a group of hereditary diseases affecting 1 in 17,000 live births worldwide. It consists of blistering of the skin and mucous membranes in response to minimal trauma. The disorder seriously affects the patient's quality of life. Diagnosis is based on immunofluorescence mapping and electron microscopy. Treatment is symptomatic, although new cellular and molecular therapies are currently under investigation. This review covers aspects of the molecular biology, clinical presentation, diagnosis, and treatment of epidermolysis bullosa relevant to improving the care for affected patients.
Related Concept Videos
Clinical Applications of Epidermal Stem Cells
Renewal of Skin Epidermal Stem Cells
Desmosomes
Long-patch Base Excision Repair

