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Nanomanipulation of Single RNA Molecules by Optical Tweezers
Published on: August 20, 2014
The adenosine wedge: a new structural motif in ribosomal RNA
Matthieu G Gagnon1, Sergey V Steinberg
1Departement de Biochimie, Universite de Montreal, Montreal, Quebec H3C 3J7, Canada.
Abstract:
Here, we present a new recurrent RNA arrangement, the so-called adenosine wedge (A-wedge), which is found in three places of the ribosomal RNA in both ribosomal subunits. The arrangement has a hierarchical structure, consisting of elements previously described as recurrent motifs, namely, the along-groove packing motif, the A-minor and the hook-turn. Within the A-wedge, these elements are involved in different types of cause-effect relationships, providing together for the particular tertiary structure of the motif.
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