Related Experiment Video
Updated: Jun 17, 2026

Induction and Assessment of Levodopa-induced Dyskinesias in a Rat Model of Parkinson's Disease
Published on: October 14, 2021
Dopamine agonist induced compulsive eating behaviour in a Parkinson's disease patient
Waqas Khan1, Abdul Qayyum Rana
1Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, FitzGerald Building, 150 College Street, Toronto, ON, M5S-3E2, Canada.
Case Description:
A patient diagnosed with type 2 diabetes mellitus and Parkinson's disease developed a compulsive eating disorder when treated with a dopamine agonist, pramipexole. The patient had no history of psychiatric illnesses and upon the discontinuation of pramipexole his abnormal behavioural symptoms were resolved.
Conclusion:
Physicians treating Parkinson's disease patients with dopamine replacement therapy should inquire about the development of any compulsive behaviours. Although uncommon, many of these non-motor symptoms go undiagnosed and can have a detrimental impact on a patient's quality of life.
Related Concept Videos
Parkinson's Disease: Treatment
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of its...
Parkinson's Disease: Overview
Parkinson Disease ll: Pathophysiology
Parkinson Disease l: Introduction
Chemotherapy-Induced Nausea and Vomiting: Dopamine Receptor Antagonists
Phenothiazines, such as prochlorperazine...
Binge Eating Disorders

