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Related Experiment Video

Updated: Jun 17, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Sturge-Weber syndrome: decrease in intraocular pressure after transpupillary thermotherapy for diffuse choroidal

Joël Gambrelle¹, Tero Kivelä, Jean-Daniel Grange

¹Department of Ophthalmology, Morvan Hospital, Brest, France. joel.gambrelle@hotmail.fr

Acta Ophthalmologica

|December 31, 2009

Summary

Transpupillary thermotherapy (TTT) effectively reduced intraocular pressure (IOP) in patients with Sturge-Weber syndrome (SWS) and late-onset juvenile glaucoma (LOJG). This treatment for diffuse choroidal haemangioma (DCH) also prevented complications.

Related Experiment Videos

Last Updated: Jun 17, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Area of Science:

Ophthalmology
Medical Laser Applications

Background:

Sturge-Weber syndrome (SWS) can lead to late-onset juvenile glaucoma (LOJG) and diffuse choroidal haemangioma (DCH).
Uncontrolled intraocular pressure (IOP) in LOJG poses a risk of vision loss.

Observation:

Two patients with SWS, DCH, and uncontrolled LOJG underwent transpupillary thermotherapy (TTT).
TTT involved selective, partial destruction of DCH using an 810 nm infrared diode laser in multiple sessions.
Laser parameters were adjusted to achieve tumor discoloration without causing complications.

Findings:

TTT resulted in normalization of IOP in both patients.
The progression of LOJG was halted during follow-up periods of up to 6 years.
No visual loss or other complications were observed post-treatment.

Implications:

TTT is a viable therapeutic option for managing both DCH and LOJG in SWS patients.
This approach may prevent exudative retinal detachment associated with DCH.
TTT offers a single-modality treatment for complex ocular conditions in SWS.