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[Salinomycin and semduramicin in different concentrations on the broilers eimeriosis control].

Giankleber Strumielo Diniz1, Anderlise Borsoi, Juarez Morbini Lopes

  • 1Universidade Estadual de Londrina, Londrina, Brazil. giankleber@hotmail.com

Revista Brasileira De Parasitologia Veterinaria = Brazilian Journal of Veterinary Parasitology : Orgao Oficial Do Colegio Brasileiro De Parasitologia Veterinaria
|December 31, 2009
PubMed
Summary

The combination of salinomycin and semduramicin effectively controlled coccidiosis in broiler chickens, even at lower doses. This drug combination offers a viable strategy for managing Eimeria infections in poultry.

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Area of Science:

  • Veterinary Parasitology
  • Poultry Science
  • Antiparasitic Drug Research

Context:

  • Coccidiosis, caused by Eimeria species, is a significant parasitic disease in broiler chickens, leading to substantial economic losses.
  • Effective control strategies are crucial for maintaining poultry health and productivity.
  • Investigating novel or optimized drug combinations is essential for sustainable coccidiosis management.

Purpose:

  • To evaluate the efficacy of different dose combinations of salinomycin and semduramicin against a controlled mixed infection of Eimeria acervulina, Eimeria maxima, and Eimeria tenella in broiler chickens.
  • To determine the impact of these combinations on bird performance and lesion development.

Summary:

  • Eight hundred broiler chickens were divided into five groups and challenged with a mixed Eimeria infection. Treatments involved feed medicated with varying doses of salinomycin and semduramicin.
  • Performance data (weight gain, feed conversion) and lesion scores were recorded. All treated groups showed improved weight gain at 21 days, with significant differences noted in specific groups at 35 days.
  • The combination of 30 ppm salinomycin and 15 ppm semduramicin (T3) and 40 ppm salinomycin and 15 ppm semduramicin (T5) demonstrated significant reductions in lesion scores across all three Eimeria species. T5 showed particular effectiveness against Eimeria tenella.

Impact:

  • The study suggests that lower-than-usual doses of salinomycin and semduramicin, when used in combination, can be an effective option for coccidiosis control in broiler chickens.
  • These findings provide valuable insights for developing optimized therapeutic strategies to combat Eimeria infections in poultry farming.
  • This research contributes to the sustainable management of poultry health and economic viability in the face of parasitic disease challenges.