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Related Experiment Video

Updated: Jun 17, 2026

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability

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Published on: July 25, 2025

Short segment coronal plane deformity after two-level lumbar total disc replacement.

Alexander C Ching¹, Christof Birkenmaier, Robert A Hart

¹Department of Orthopaedics and Rehabilitation, Oregon Health Sciences University, Portland, OR 97229, USA.

|January 1, 2010

Summary

This summary is machine-generated.

Two-level lumbar disc arthroplasty failures were observed, primarily due to coronal instability. This suggests increased risks with multilevel disc arthroplasty compared to single-level procedures.

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Area of Science:

Spine surgery
Biomedical engineering
Orthopedic surgery

Background:

Arthrodesis is standard for degenerative disc disease, but causes adjacent level issues.
Total disc arthroplasty (TDA) aims to reduce these problems.
Single-level TDA shows promise, leading to exploration of multilevel applications.

Observation:

This case series reports on 4 patients with failed two-level lumbar disc arthroplasty.
Failures occurred within 11-13 months, presenting as increased back pain and radicular symptoms.
Coronal instability due to prosthesis deviation was the primary failure mechanism.

Findings:

Two-level lumbar disc arthroplasty demonstrated a significant failure rate in this series.
Coronal instability appears to be a key concern in multilevel TDA.
The failure rate in local cases was 29% of all two-level CHARITE arthroplasties.

Implications:

Multilevel TDA may carry a higher risk of coronal plane instability.
The findings warrant attention from the spine surgery community regarding multilevel TDA risks and costs.
Further investigation into the biomechanics and indications for multilevel TDA is recommended.