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A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
Heparin-induced thrombocytopenia associated with pulmonary embolism
1Section of Emergency Medicine and Cardiology, Department of Internal Medicine, Livorno Hospital, Livorno, Italy. nimumoli@tiscali.it
Abstract:
Type II heparin-induced thrombocytopenia (HIT) is a potentially severe adverse effect of heparin treatment triggered by an immune response. Although most cases occur in patients receiving unfractioned heparin, HIT can also arise after low-molecular-weight heparin (LMWH). We report a case of HIT in a postoperative orthopedic 75-year-old woman in treatment with LMWH (nadroparin) complicated by pulmonary embolism and treated successfully with recombinant hirudin. Early recognition and proper treatment are fundamental for the management of this life-threatening disorder.
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