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Sleep disordered breathing is associated with appropriate implantable cardioverter defibrillator therapy in
Luca Tomaello1, Luisa Zanolla, Corrado Vassanelli
1Department of Biomedical and Surgical Sciences, University of Verona, Italy. luca.tomaello@libero.it
Insights
Sleep disordered breathing (SDB) affects most patients with implantable cardioverter defibrillators (ICDs) and congestive heart failure (CHF). SDB severity correlates with appropriate ICD shocks, indicating increased arrhythmia risk.
Area of Science:
- Cardiology
- Sleep Medicine
- Medical Devices
Background:
- Implantable cardioverter defibrillators (ICDs) are common in congestive heart failure (CHF) patients.
- Sleep disordered breathing (SDB) is prevalent in this patient population.
Purpose of the Study:
- To determine the prevalence of SDB in CHF patients with ICDs.
- To assess the impact of SDB on appropriate ICD discharges.
Main Methods:
- Polysomnography was used to study 22 consecutive patients with systolic CHF (LVEF < 45%) and ICDs.
Main Results:
- SDB was detected in 77.2% of patients (AHI ≥ 10 events/hour).
- Apnea-hypopnea index (AHI) and sleep hypoxia severity correlated with appropriate ICD discharges, independent of LVEF and NYHA class.
Conclusions:
- SDB is frequent in ICD recipients with systolic CHF.
- SDB may elevate the risk of ventricular arrhythmias and necessitate appropriate ICD interventions.
Background:
Implantable cardioverter defibrillators (ICDs) are increasingly employed in patients affected by congestive heart failure (CHF) and sleep disordered breathing (SDB) is frequent in this population.
Hypothesis:
To investigate SDB prevalence and influence on appropriate ICD discharges in CHF patients.
Methods:
A total of 22 consecutive ICD patients with systolic CHF (left ventricular ejection fraction [LVEF]< 45%) were studied by polysomnography.
Results:
A total of 17 (77.2%) showed SDB (apnea-hypopnea index [AHI]_ 10 events/hour). After controlling for LVEF and New York Heart Association (NYHA) class, AHI and severity of hypoxia during sleep results correlated to appropriate ICD discharges (r = 0.718; P < .001, r = - 0.619; P = .003, respectively).
Conclusions:
Sleep disordered breathing is frequent in ICD recipients due to left systolic ventricular dysfunction and may increase the risk of ventricular arrhythmia and appropriate ICD discharges.
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