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Published on: October 20, 2023
Evidence that atypical juxtafacet cysts are joint derived
Robert J Spinner1, Marie-Noëlle Hébert-Blouin, Timothy P Maus
1Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA. spinner.robert@mayo.edu
Juxtafacet cysts (JFCs) are believed to originate from spinal facet joints. This study confirms joint connections in atypical spinal JFCs, supporting a unified theory of cyst formation in all locations.
Area of Science:
- Spine surgery
- Orthopedic pathology
- Radiology
Background:
- Juxtafacet cysts (JFCs) in typical spinal locations are increasingly recognized as having joint connections.
- The origin and pathogenesis of JFCs in unusual or atypical locations remain less understood.
- A unified theory of JFC formation, encompassing both typical and atypical presentations, is needed.
Purpose of the Study:
- To investigate the pathogenesis of spinal juxtafacet cysts, particularly those in unusual locations.
- To determine if spinal JFCs, including atypical presentations, are consistently derived from the associated facet joints.
- To identify and characterize joint connections in spinal JFCs to support a unified theory of their formation.
Main Methods:
- A comprehensive literature review was conducted to identify case reports of spinal intraneural cysts.
- Analysis of far-lateral (extraforaminal) JFCs treated at the authors' institution and reported in the literature.
- Specific examination for the presence of joint connections in all reviewed cases, including arthrography where applicable.
Main Results:
- Three case reports of spinal intraneural JFCs without reported joint connections were identified.
- Six cases of far-lateral JFCs treated at the institution all demonstrated joint connections.
- Arthrography confirmed facet-cyst communication in two new cases; only one prior literature case recognized this connection.
Conclusions:
- All juxtafacet cysts (JFCs), regardless of location (intraneural or extraneural), are hypothesized to be joint-derived.
- This finding supports a unified articular (synovial) theory for JFC formation, analogous to ganglion cysts in the limbs.
- Understanding JFC pathogenesis aids in targeted treatment, improved surgical outcomes, and reduced recurrence rates.
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