Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Myocardial imaging artifacts caused by mitral valve annulus calcification.

L E Wagoner1, A Movahed, W C Reeves

  • 1Department of Medicine, East Carolina University School of Medicine, Greenville, North Carolina 27858-5354.

Clinical Nuclear Medicine
|February 1, 1991
PubMed
Summary

Imaging artifacts in thallium-201 myocardial perfusion studies can mimic coronary artery disease. A calcified mitral valve annulus caused a false defect, highlighting the need for careful interpretation in cardiac imaging.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Experimental Evaluation of Mouse Hind Paw Edema Induced by Iranian Naja oxiana Venom.

Archives of Razi Institute·2021
Same author

Resveratrol protects adult cardiomyocytes against oxidative stress mediated cell injury.

Archives of biochemistry and biophysics·2012
Same author

Certain bacteriostatic agents added to sera used in diagnostic tests for neurotropic virus infections.

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)·2010
Same author

Epidemiologic studies of encephalitis in the San Joaquin Valley of California, 1943, with the isolation of viruses from mosquitoes.

American journal of hygiene·2010
Same author

Western equine encephalomyelitis virus in the blood of experimentally inoculated chickens.

The Journal of experimental medicine·2010
Same author

St. Louis encephalitis virus in the blood of experimentally inoculated fowls and mammals.

The Journal of experimental medicine·2010

Area of Science:

  • Cardiology
  • Medical Imaging
  • Diagnostic Accuracy

Background:

  • Myocardial perfusion imaging with thallium-201 is a key diagnostic tool for coronary artery disease.
  • Accurate interpretation relies on understanding potential imaging artifacts.
  • Identifying artifacts is crucial for reliable diagnosis.

Observation:

  • Three patients presented with apparent moderate, fixed myocardial perfusion defects.
  • These defects were located on the posterolateral and inferoposterior walls of the left ventricle.
  • The observed defects were not indicative of actual myocardial scarring.

Findings:

  • The "defects" were identified as imaging artifacts.
  • A heavily calcified mitral valve annulus was the cause of the artifact.

Related Experiment Videos

  • This artifact mimicked a true myocardial scar.

    • Implications:

    • Awareness of mitral valve annulus calcification as an artifact source is essential.
    • This knowledge can prevent misdiagnosis of coronary artery disease.
    • Improved diagnostic accuracy in myocardial perfusion studies is achievable.