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Updated: Jun 17, 2026
11:17
Comparative Analysis of Human Growth Hormone in Serum Using SPRi, Nano-SPRi and ELISA Assays
Published on: January 7, 2016
[Growth hormone revisited]
Jesús Devesa1, Pablo Devesa, Pedro Reimunde
1Departamento de Fisiología, Facultad de Medicina, Santiago de Compostela, España; Centro Médico Proyecto Foltra, Cacheiras, Teo, A Coruña, España. jesus.devesa@usc.es
Medicina Clinica
|January 5, 2010
Summary
Growth hormone (GH) has diverse roles beyond classic functions, including neuroprotection and cardiovascular benefits. Exogenous GH shows potential for treating brain injury, promoting neural regeneration, and aiding tissue repair without apparent oncogenic risk.
Area of Science:
- Endocrinology
- Neuroscience
- Cardiovascular Science
Context:
- Growth hormone (GH) exhibits pleiotropic effects beyond its metabolic roles.
- GH is expressed at both pituitary and peripheral levels.
- Emerging research highlights novel functions of GH in various physiological systems.
Purpose:
- To review the multifaceted roles of growth hormone (GH).
- To explore the neurotropic and cardiovascular effects of GH.
- To discuss the potential clinical applications of exogenous GH administration.
Summary:
- GH promotes neural precursor proliferation and survival, offering neuroprotective benefits.
- Cardiovascular effects include improved lipid profiles, reduced cardiac risk factors, enhanced endothelial function, and potentiation of revascularization.
- Exogenous GH administration appears distinct from autocrine GH regarding oncogenesis.
- GH demonstrates potential in treating brain injury, neural regeneration, perinatal anoxia, ischemic conditions, bone healing, and ulcer recovery.
Impact:
- Highlights the therapeutic potential of GH in neurological and cardiovascular diseases.
- Suggests novel applications for GH in regenerative medicine and trauma recovery.
- Provides a comprehensive overview of GH's expanded physiological and clinical relevance.
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