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Related Concept Videos

Skeletal Muscle Anatomy00:55

Skeletal Muscle Anatomy

Skeletal muscle is the most abundant type of muscle in the body. Tendons are the connective tissue that attaches skeletal muscle to bones. Skeletal muscles pull on tendons, which in turn pull on bones to carry out voluntary movements.
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Overview of Skeletal Muscle01:15

Overview of Skeletal Muscle

Skeletal muscles are composed of a bundle of muscle fibers and are attached to bones through tendons. Each skeletal muscle fiber is a single muscle cell. The sarcolemma, the plasma membrane of a skeletal muscle cell, consists of a lipid bilayer and glycocalyx that supports muscle fibers. The sarcolemma extends into the muscle cells to form tubular structures called transverse or T-tubules. Each side of the T-tubules consists of a membrane-bound structure called the sarcoplasmic reticulum,...
Microscopic Anatomy of Skeletal Muscles01:13

Microscopic Anatomy of Skeletal Muscles

Skeletal muscle cells, also called muscle fibers, are distinctly elongated, multi-nucleated, slender biological units. They are packed with specialized structures designed to facilitate their primary function, which is contraction.
The muscle sarcolemma is a plasma membrane enclosing each muscle cell that conducts electrical signals called action potentials. The sarcolemma extends into the cell to form T-tubules, ensuring the neural impulses are uniformly distributed across the entire muscle...
What is the Skeletal System?01:02

What is the Skeletal System?

Overview
Bone Structure01:55

Bone Structure

Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.

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Related Experiment Video

Updated: Jun 17, 2026

A Novel Application of Musculoskeletal Ultrasound Imaging
10:53

A Novel Application of Musculoskeletal Ultrasound Imaging

Published on: September 17, 2013

Musculoskeletal molecular imaging: a comprehensive overview.

Marie K Reumann1, Mitchell C Weiser, Philipp Mayer-Kuckuk

  • 1Bone Cell Biology and Imaging Laboratory, Caspary Research Building, Rm. 623, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.

Trends in Biotechnology
|January 5, 2010
PubMed
Summary

Molecular imaging offers a non-invasive way to study bone and joint diseases. This review highlights its use in understanding skeletal conditions and developing new therapies for orthopedics and rheumatology.

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Last Updated: Jun 17, 2026

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Non-invasive Skeletal Muscle Quantification in Small Animals Using Micro-computed Tomography

Published on: November 8, 2024

Area of Science:

  • Biomedical imaging
  • Musculoskeletal biology
  • Molecular biology

Background:

  • Molecular imaging complements traditional anatomical imaging by visualizing molecular and cellular processes in vivo.
  • Its application in musculoskeletal biology is an emerging field with significant potential.

Purpose of the Study:

  • To review the emerging applications of molecular imaging in musculoskeletal biology.
  • To highlight the utility of bioluminescence and fluorescence techniques in studying skeletal processes.

Main Methods:

  • Review of existing literature on molecular imaging in musculoskeletal research.
  • Focus on bioluminescence and fluorescence imaging techniques.

Main Results:

  • Molecular imaging enables in vivo studies of osteoblast/osteoclast activity, hormone function, and pathological bone/cartilage destruction.
  • Applications include skeletal gene/cell therapy, osteolysis, and osteomyelitis research.
  • Demonstrated feasibility across diverse musculoskeletal conditions like fracture, arthritis, and bone cancer.

Conclusions:

  • Musculoskeletal molecular imaging is a feasible research tool for various skeletal conditions.
  • These advances hold promise for innovative clinical imaging in orthopedics, rheumatology, and oncology.