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Anti-inflammatory activity of roots of Ecbolium viride (Forsk) Merrill
1Department of Pharmaceutical Chemistry, Ultra College of Pharmacy, Madurai 625 020, Tamil Nadu, India.
Ethnopharmacological Relevance:
Traditionally the aqueous extracts of dried roots of the plant Ecbolium viride are used for menorrhagia, rheumatism and jaundice.
Aim Of The Study:
The aim was to evaluate the anti-inflammatory activity of Ecbolium viride extract in an in vivo model.
Materials And Methods:
The ethyl acetate fraction of Ecbolium viride root extract was prepared and administered orally to rats. The anti-inflammatory activity of Ecbolium viride was determined by carrageenan-induced paw edema and cotton pellet granuloma models.
Results:
Oral administration of Ecbolium viride extract reduced inflammation significantly (P<0.01) in both the carageenan paw edema and the cotton pellet granuloma models.
Conclusions:
The results of the study supported the traditional use of Ecbolium viride in the treatment for inflammatory disease.
