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Published on: July 17, 2018
Paralemnolins J-P, new sesquiterpenoids from the soft coral Paralemnalia thyrsoide
Guey-Horng Wang1, Ho-Cheng Huang, Jui-Hsin Su
1Department of Cosmetic Science, Chia-Nan University of Pharmacy and Science, Taiwan.
Abstract:
Six new sesquiterpenoids, paralemnolins J-O (1-6), along with one novel norsesquiterpenoid, paralemnolin P (7), have been isolated from the soft coral Paralemnalia thyrsoides. The structures of metabolites 1-7 were established on the basis of extensive NMR study and chemical methods. The structure of 5 was further confirmed by a single-crystal X-ray analysis. Cytotoxicity of these metabolites toward a limited panel of cancer cell lines also is described.
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