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Eosinophilic gastroenteritis with eosinophilic dermatitis
Jae Myung Cha1, Joung Il Lee, Kwang Ro Joo
1Department of Internal Medicine, East-West Neo Medical Center, KyungHee University College of Medicine, Seoul, Korea. dramc@hanmail.net
Yonsei Medical Journal
|January 5, 2010
Summary
Eosinophilic gastroenteritis (EG) can mimic appendicitis. This case highlights EG with eosinophilic dermatitis, a rare presentation successfully treated with steroids.
Area of Science:
- Gastroenterology
- Dermatology
- Pathology
Background:
- Eosinophilic gastroenteritis (EG) involves eosinophilic infiltration of the gastrointestinal tract, often presenting with vague abdominal symptoms.
- Prompt diagnosis of EG is crucial to prevent misdiagnosis and ensure appropriate treatment.
- Peripheral eosinophilia and gastrointestinal symptoms warrant a high index of suspicion for EG.
Observation:
- A 24-year-old woman presented with acute right lower quadrant pain, initially diagnosed as appendicitis.
- Laparoscopic appendectomy revealed bowel edema and ascites, but no suppurative appendicitis.
- Post-surgery, the patient developed persistent eosinophilia, eosinophilic ascites, and eosinophilic infiltration in the appendix, gastroduodenal mucosa, and skin.
Findings:
- The patient was diagnosed with eosinophilic gastroenteritis (EG) and eosinophilic dermatitis.
- Histopathology confirmed eosinophilic infiltration in multiple tissues.
- The condition resolved with low-dose steroid treatment.
Implications:
- This case represents a novel co-occurrence of EG and eosinophilic dermatitis.
- It underscores the importance of considering EG in patients with unexplained gastrointestinal and systemic eosinophilia.
- The findings suggest a potential link between gastrointestinal and cutaneous eosinophilic inflammation.
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