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Acquired ichthyosis associated with type 1 diabetes mellitus
Hatice Sanli1, Bengü Nisa Akay, Bilge Bulbul Sen
1Department of Dermatology; Ankara University School of Medicine; Ankara, Turkey.
Dermato-Endocrinology
|January 5, 2010
Summary
Acquired ichthyosis, a rare skin condition, can be linked to new-onset diabetes mellitus. Skin scaling resolved completely after blood glucose regulation with insulin therapy, highlighting a potential connection.
Area of Science:
- Dermatology
- Endocrinology
Background:
- Acquired ichthyosis presents as symmetric skin scaling.
- It is associated with various conditions like malignancies, infections, and autoimmune diseases.
- Association with diabetes mellitus is exceptionally rare, with only one prior report.
Purpose of the Study:
- To report a novel case of acquired ichthyosis and palmoplantar keratoderma linked to new-onset diabetes mellitus.
- To investigate the resolution of these dermatological conditions upon glycemic control.
Main Methods:
- Case report of a patient with new-onset diabetes mellitus and acquired ichthyosis.
- Clinical presentation and skin biopsy findings documented.
- Treatment involved insulin therapy for blood glucose regulation.
Main Results:
- The patient presented with generalized acquired ichthyosis and palmoplantar keratoderma.
- Skin manifestations resolved completely following effective blood glucose management.
- Skin biopsy confirmed the diagnosis of ichthyosis.
Conclusions:
- New-onset diabetes mellitus can manifest with acquired ichthyosis and palmoplantar keratoderma.
- Effective glycemic control through insulin therapy can lead to complete resolution of these dermatological symptoms.
- This case underscores the importance of considering metabolic disorders in the differential diagnosis of acquired ichthyosis.
Keywords:
acquired ichthyosisdiabetes mellitusinsulin deficiencykeratinization disorderpalmoplantar keratodermaMore Related Videos
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