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Internal Functionalization and Surface Modification of Vinylsilsesquioxane Nanoparticles.

Eric M Brozek1, Ilya Zharov

  • 1Department of Chemistry, University of Utah, Salt Lake City, Utah 84112.

Chemistry of Materials : a Publication of the American Chemical Society
|January 5, 2010
PubMed
Summary

Novel hybrid silsesquioxane nanoparticles were created by modifying the interior vinyl groups. These accessible internal groups allow for easy bromination or hydroboration, enabling diverse hybrid organosilica nanoparticle synthesis.

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Area of Science:

  • Materials Science
  • Nanotechnology
  • Organic Chemistry

Background:

  • Silsesquioxane nanoparticles offer a versatile platform for material modification.
  • Functionalizing the interior of nanoparticles presents unique synthetic challenges.
  • Developing methods for creating complex hybrid organosilica nanoparticles is of significant interest.

Purpose of the Study:

  • To synthesize novel hybrid silsesquioxane nanoparticles.
  • To demonstrate the accessibility and reactivity of internal vinyl groups.
  • To enable further functionalization of nanoparticle surfaces.

Main Methods:

  • Covalent modification of interior vinyl groups within 237 nm spherical vinylsilsesquioxane nanoparticles.
  • Surface functionalization under mild reaction conditions.

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  • Thermogravimetric analysis (TGA) and elemental analysis for characterization.

    • Main Results:

    • Successfully synthesized hybrid silsesquioxane nanoparticles with modified interiors.
    • Bromination yielded nanoparticles with 59.9 wt% bromine; hydroboration yielded nanoparticles with 3.6 wt% boron.
    • Demonstrated high accessibility of internal vinyl groups for chemical modification.
    • Confirmed that brominated and boronated nanoparticle surfaces remain unhindered for subsequent amination.

    Conclusions:

    • The interior vinyl groups of silsesquioxane nanoparticles are readily accessible for chemical modification.
    • This approach facilitates the creation of diverse hybrid organosilica nanoparticles with complex structures.
    • The functionalized nanoparticles serve as platforms for further surface modifications, such as amination.