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Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
Published on: September 25, 2019
Acute brain MRI-DWI patterns and stroke recurrence after mild-moderate stroke.
Jaume Roquer1, A Rodríguez-Campello, E Cuadrado-Godia
1NeuroMar Research Group, Stroke Unit, Department of Neurology, Hospital del Mar-IMIM, Barcelona, Spain. jroquer@hospitaldelmar.cat
Journal of Neurology
|January 5, 2010
Summary
Diffusion-weighted imaging (DWI) patterns in acute mild-moderate stroke predict recurrence risk. Multiple lesions or lesions in different territories indicate a higher risk of future ischemic events.
Area of Science:
- Neurology
- Radiology
- Cardiovascular Medicine
Background:
- Diffusion-weighted imaging (DWI) identifies acute ischemic brain lesions.
- These lesions are known predictors of future ischemic events in transient ischemic attack and minor stroke patients.
Purpose of the Study:
- To analyze brain MRI-DWI patterns in mild-moderate stroke patients.
- To define acute patterns associated with increased long-term stroke recurrence risk (6-36 months).
Main Methods:
- Retrospective review of 253 mild-moderate stroke patients (NIHSS 1-7) with acute MRI-DWI lesions.
- Analysis of lesion number, location, age, and affected arterial territories to define three patterns.
- Cox regression analysis to assess the impact of patterns on recurrence.
Main Results:
- Recurrence occurred in 15.0% of patients.
- Multiple lesions (Pattern 1) significantly increased recurrence risk (OR: 2.49, p=0.008).
- Multiple lesions in different territories or of different ages (Pattern 3) showed the highest recurrence rate (OR: 2.85, p=0.008).
Conclusions:
- Acute brain MRI-DWI patterns are valuable for identifying mild-moderate stroke patients at high risk of recurrence.
- Specific lesion characteristics on DWI can stratify patients for closer monitoring and intervention.
- This imaging approach aids in predicting long-term stroke outcomes.
