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Sleep duration and hyperglycemia among obese and nonobese children aged 3 to 6 years
Zhen Tian1, Tao Ye, Xiaoyan Zhang
1Tianjin Women and Children's Health Center, Tianjin, China.
Insights
Shorter sleep duration is linked to a higher risk of hyperglycemia in young Chinese children. This association persists even after accounting for obesity and other factors, highlighting sleep
Area of Science:
- Pediatric Endocrinology
- Sleep Medicine
- Public Health
Background:
- Childhood obesity is a growing concern with potential metabolic consequences.
- Hyperglycemia in children can indicate underlying metabolic dysfunction.
- Understanding modifiable risk factors for hyperglycemia is crucial for early intervention.
Purpose of the Study:
- To examine the relationship between sleep duration and hyperglycemia risk in preschool-aged Chinese children.
- To determine if sleep duration is an independent risk factor for hyperglycemia in this population.
Main Methods:
- A population-based cross-sectional study involving 71 kindergartens in Tianjin, China.
- Recruitment of 619 obese and 617 nonobese children aged 3-6 years, matched by age.
- Assessment of sleep duration and measurement of fasting glucose levels to define hyperglycemia (≥100 mg/dL).
Main Results:
- Obese children exhibited significantly shorter sleep durations (< or =8 hours) compared to nonobese children.
- Children sleeping 8 hours or less had a 1.65-fold increased likelihood of hyperglycemia compared to those sleeping 9-10 hours (OR, 1.65; 95% CI, 1.12-2.45), even after adjustments.
- The association remained significant in stratified analyses, with obese children sleeping <=8 hours showing a 2.12-fold increased risk (OR, 2.12; 95% CI, 1.06-4.21).
Conclusions:
- Shorter sleep duration is significantly associated with an elevated risk of hyperglycemia in preschool Chinese children.
- The findings suggest that inadequate sleep may contribute to metabolic dysregulation in this age group.
- Further research is needed to explore the role of adequate sleep in maintaining normal glucose levels, particularly in overweight and obese children.
Objective:
To investigate the association between sleep duration and risk of hyperglycemia among preschool Chinese children.
Design:
A population-based cross-sectional study.
Setting:
Seventy-one randomly selected kindergartens in Tianjin, China.
Participants:
Six hundred nineteen obese (body mass index z score > or =1.65) and 617 nonobese (body mass index z score <1.65) children aged 3 to 6 years were recruited and matched by age. Main Exposure Sleep duration.
Main Outcome Measures:
Hyperglycemia, defined as a fasting glucose level of 100 mg/dL or higher.
Results:
Obese children were more likely to have shorter sleep duration (< or =8 hours) compared with their nonobese counterparts (P < .001). Compared with those who slept for 9 or 10 hours per night, those who slept for 8 hours or less had a significantly higher likelihood of having hyperglycemia, controlling for age and sex (odds ratio [OR], 1.65; 95% confidence interval [CI], 1.12-2.45). After further adjustment for other potential confounders, the association still remained statistically significant (OR, 1.64; 95% CI, 1.09-2.46). In the stratified multivariable analyses, those who were obese and slept for 8 hours or less had an increased risk of having hyperglycemia (OR, 2.12; 95% CI, 1.06-4.21) compared with those who were nonobese and slept for 9 hours or more.
Conclusions:
Shorter sleep duration is associated with an increased risk of having hyperglycemia among preschool Chinese children. Whether adequate sleep may help maintain euglycemia among children, especially for those who are overweight or obese, warrants further investigation.
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