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Related Concept Videos

Coronary Circulation01:21

Coronary Circulation

The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...

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Related Experiment Video

Updated: Jun 17, 2026

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit
07:04

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit

Published on: April 15, 2021

Spontaneous multivessel coronary artery dissection.

Manreet Kanwar1, Nikita Gill

  • 1Department of Medicine, St. John Hospital and Medical Center, 22101 Moross Road, 2nd Floor VEP, Cardiac Cath Lab, Detroit, MI 48236, USA. manreet.kanwar@stjohn.org

The Journal of Invasive Cardiology
|January 6, 2010
PubMed
Summary
This summary is machine-generated.

Spontaneous coronary artery dissection is rare, especially in men. This case highlights a 54-year-old methamphetamine user experiencing multivessel dissection, treated successfully with coronary artery bypass grafting.

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Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

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Last Updated: Jun 17, 2026

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit
07:04

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit

Published on: April 15, 2021

Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

Area of Science:

  • Cardiology
  • Vascular Medicine

Background:

  • Spontaneous coronary artery dissection (SCAD) is a rare condition, typically affecting peripartum women, often involving a single coronary vessel.
  • While SCAD in men is uncommon, multivessel involvement presents a severe, life-threatening scenario.

Observation:

  • A 54-year-old male with diabetes, hypertension, and methamphetamine abuse presented with cardiac arrest, ventricular tachycardia, and ECG changes.
  • Cardiac catheterization revealed spontaneous dissection in the left anterior descending artery, first diagonal branch, and the right coronary artery, alongside atherosclerotic disease.

Findings:

  • The patient experienced multivessel spontaneous coronary artery dissection, a presentation rarely reported in association with methamphetamine abuse.
  • Successful treatment was achieved with a two-vessel coronary artery bypass grafting (CABG).

Implications:

  • This case underscores the potential association between methamphetamine use and severe, multivessel spontaneous coronary artery dissection.
  • Highlights the importance of considering substance abuse in the differential diagnosis of SCAD, particularly in male patients presenting with acute coronary syndromes.