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Related Experiment Videos

Fluoride dentifrices: current status and prospects.

J R Mellberg1

  • 1Colgate-Palmolive Company, Technology Center, Piscataway, NJ 08854.

International Dental Journal
|February 1, 1991
PubMed
Summary
This summary is machine-generated.

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Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995)·1997
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Archivos latinoamericanos de nutricion·1992
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Journal of dental research·1992
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Modern toothpastes, with effective fluoride agents like sodium monofluorophosphate, significantly reduce dental caries. Increasing fluoride concentration enhances anti-caries effects, with additives like pyrophosphate showing promise for combined benefits.

Area of Science:

  • Dental Science
  • Materials Science

Background:

  • Toothpastes evolved from ineffective formulations to highly effective products credited with reducing dental caries.
  • Early toothpastes used sodium fluoride, later replaced by stannous fluoride, sodium monofluorophosphate, and amine fluoride.

Purpose of the Study:

  • To review the development and effectiveness of fluoride agents in toothpastes.
  • To assess the impact of fluoride concentration and additive agents on anti-caries efficacy.

Main Methods:

  • Review of historical toothpaste formulations and fluoride agents.
  • Analysis of clinical caries trials and in vitro/in vivo studies on toothpaste additives.

Main Results:

  • Sodium monofluorophosphate is compatible with various abrasives, though sodium fluoride formulations are increasing.

Related Experiment Videos

  • Clinical trials show minimal difference in effectiveness between different fluoride agents when properly formulated.
  • Increased fluoride concentration enhances anti-caries effects.
  • Additives like pyrophosphate do not interfere with fluoride's anti-caries activity and can provide calculus control.

    • Conclusions:

    • Toothpaste formulation advancements have led to significant reductions in dental caries.
    • Optimizing fluoride concentration and ensuring compatibility with other agents are key to effective toothpaste development.
    • Future research utilizing modern evaluation methods will likely yield new toothpaste formulations with multiple active agents.