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Is there a link between wheezing in early childhood and adverse birth outcomes? A systematic review
Evridiki Patelarou1, Maria Chochlidaki, Victoria Vivilaki
1University Hospital of Heraklion, Crete, Greece. patelarou@edu.med.uoc.gr
Abstract:
We aimed to provide a summary of the existing published knowledge on the association between adverse birth outcomes and the development of wheezing during the first two years of life. We carried out a systematic review of epidemiological studies within the MEDLINE database. Epidemiological studies on human subjects, published in English, were included in the review. A comprehensive literature search yielded 72 studies for further consideration. Following the application of the eligibility criteria we identified nine studies. A positive association and an excess risk of wheezing during the first two years of life were revealed for adverse birth outcomes.
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