Related Experiment Video
Updated: Jun 17, 2026

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
Published on: August 4, 2022
Impact of co-occurring psychiatric disorders on retention in a methadone maintenance program: an 18-month follow-up
Mònica Astals1, Laura Díaz, Antònia Domingo-Salvany
1Institute of Psychiatry and Addiction, Hospital del Mar and Institut Municipal d'Investigació Mèdica, Barcelona, Spain. mastals@imas.imim.es
Abstract:
We assess the influence of co-occurring psychiatric disorders on retention in 189 opioid dependent patients in a methadone maintenance treatment (MMT) and determine the incidence of psychiatric co-morbidity during an 18-month follow-up period. About 68.5 % were retained in the MMT. Neither co-occurring mental disorders (chi-square = 0.303, df = 1, p = 0.622) nor methadone doses [85 (88.9) vs. 79.2 (85) mg/day, p = 0.672] were related to retention. In the follow-up period 19 new diagnoses were made, mainly major depression and antisocial and borderline personality disorders. Co-occurring psychiatric disorders should be assessed during MMT follow-up.
Related Concept Videos
Drug Therapy
Antianxiety Medications
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Psychosis: Goals of Pharmacotherapy
Community Based Intervention
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
Psychological and Sociocultural Causes of Schizophrenia
Drug Dependence
