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Lesion Explorer: A Video-guided, Standardized Protocol for Accurate and Reliable MRI-derived Volumetrics in Alzheimer's Disease and Normal Elderly
Published on: April 14, 2014
Computer input devices: neutral party or source of significant error in manual lesion segmentation?
James Y Chen1, F Jacob Seagull, Paul Nagy
1University of Pennsylvania, Philadelphia, USA. James_Chen@alumni.brown.edu
Journal of Digital Imaging
|January 6, 2010
Summary
Radiologists found graphics tablets more accurate for lesion contour segmentation than mice. While contour accuracy improved with tablets, area accuracy remained similar, though tablets were faster and preferred by users.
Area of Science:
- Medical Imaging Analysis
- Radiology
- Image Segmentation
Background:
- Lesion segmentation is critical for tracking diseases in medical imaging.
- Accurate boundary delineation distinguishes normal from abnormal tissue.
- Input devices impact segmentation efficiency and accuracy.
Purpose of the Study:
- To compare the accuracy and efficiency of graphics tablets versus laser optical mice for lesion segmentation.
- To evaluate radiologist preference and subjective experience with different input devices.
Main Methods:
- Eleven radiologists segmented 132 simulated lesions using both a graphics tablet and a laser optical mouse.
- Contour and area segmentation errors were quantified using root mean square error and comparison to reference lesions.
- Segmentation time and subjective user experience were recorded.
Main Results:
- Graphics tablets significantly reduced contour segmentation error compared to mice (P < 0.0001).
- Area segmentation error showed no significant difference between the two devices (P = 0.62).
- Segmentation time was significantly shorter with the graphics tablet (P = 0.011), and users overwhelmingly preferred it.
Conclusions:
- Graphics tablets offer superior accuracy for lesion contour segmentation, with a slight speed advantage.
- For lesion area segmentation, both graphics tablets and mice provide comparable accuracy.
- User preference strongly favors graphics tablets due to perceived speed, ease of use, and accuracy.

