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Updated: Jun 17, 2026
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Targeted Laser Ablation in the Embryo of Saccharina latissima
Published on: March 11, 2022
Prospects and developments in cell and embryo laser nanosurgery.
Vikram Kohli1, Abdulhakem Y Elezzabi1
1Department of Electrical and Computer Engineering, University of Alberta, Edmonton, Alberta, Canada.
Summary
Femtosecond laser pulses enable non-destructive nanosurgery on cells and embryos. This versatile tool is revolutionizing developmental biology, genetics, and zoology research.
Area of Science:
- Biotechnology
- Cell Biology
- Developmental Biology
Background:
- Growing interest in applying femtosecond (fs) laser pulses for biological research.
- Recent advancements in cell and embryo nanosurgery techniques.
Purpose of the Study:
- To review developments in fs laser applications for cell and embryo nanosurgery.
- To highlight the non-destructive capabilities of fs laser pulses in biological manipulation.
Main Methods:
- Review of studies utilizing fs laser pulses for cellular and subcellular alterations.
- Analysis of fs laser applications in simple cells and complex embryos.
Main Results:
- Fs laser pulses demonstrate non-destructive manipulation of cellular and subcellular sites.
- Successful application in both simple cells and multicompartmental embryos.
Conclusions:
- Fs laser pulses are an invaluable, non-invasive tool for developmental biologists, geneticists, cryobiologists, and zoologists.
- Integration of fs laser technology into life sciences, establishing its role alongside molecular and genetic methods.
- Fostering interdisciplinary collaborations between physicists, engineers, and biologists to address biological challenges.
