Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Enhancing Combat Surgical Readiness: The Development and Impact of the Combat Craniomaxillofacial Trauma Surgery Course.

Military medicine·2026
Same author

Designing multi-site charge-bifurcation networks in <i>de novo</i> proteins: a kinetic, statistical, and machine-learning approach.

Physical chemistry chemical physics : PCCP·2026
Same author

Recombinant Protein Nanoparticles for Dual-Stage Inhibition of SARS-CoV‑2 Infection.

ACS nanoscience Au·2026
Same author

Measuring the traction forces of upstream-migrating hematopoietic-like KG1a cells under shear flow.

Biophysical journal·2025
Same author

Hydroxy-substituted electron deficient Pd porphyrin cofactors illuminate ultrafast proton transfer reactions.

Journal of inorganic biochemistry·2025
Same author

Driving Force Dependent Photoinduced Charge Transfer Dynamics in Polymer-Wrapped Semiconducting Single-Walled Carbon Nanotubes.

Journal of the American Chemical Society·2025

Related Experiment Video

Updated: Jun 17, 2026

In Vivo Optical Imaging of Brain Tumors and Arthritis Using Fluorescent SapC-DOPS Nanovesicles
09:04

In Vivo Optical Imaging of Brain Tumors and Arthritis Using Fluorescent SapC-DOPS Nanovesicles

Published on: May 2, 2014

In vivo fluorescence imaging: a personal perspective.

P Peter Ghoroghchian1, Michael J Therien, Daniel A Hammer

  • 1Department of Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA. ppghoroghchian@partners.org

Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology
|January 6, 2010
PubMed
Summary

Polymersomes effectively deliver organic near-infrared (NIR) fluorophores for deep-tissue fluorescence imaging. This advance enhances molecular diagnostics and therapeutics in research and clinical settings.

More Related Videos

In vivo Imaging of Tumor Angiogenesis using Fluorescence Confocal Videomicroscopy
05:08

In vivo Imaging of Tumor Angiogenesis using Fluorescence Confocal Videomicroscopy

Published on: September 11, 2013

Non-invasive In Vivo Fluorescence Optical Imaging of Inflammatory MMP Activity Using an Activatable Fluorescent Imaging Agent
06:46

Non-invasive In Vivo Fluorescence Optical Imaging of Inflammatory MMP Activity Using an Activatable Fluorescent Imaging Agent

Published on: May 8, 2017

Related Experiment Videos

Last Updated: Jun 17, 2026

In Vivo Optical Imaging of Brain Tumors and Arthritis Using Fluorescent SapC-DOPS Nanovesicles
09:04

In Vivo Optical Imaging of Brain Tumors and Arthritis Using Fluorescent SapC-DOPS Nanovesicles

Published on: May 2, 2014

In vivo Imaging of Tumor Angiogenesis using Fluorescence Confocal Videomicroscopy
05:08

In vivo Imaging of Tumor Angiogenesis using Fluorescence Confocal Videomicroscopy

Published on: September 11, 2013

Non-invasive In Vivo Fluorescence Optical Imaging of Inflammatory MMP Activity Using an Activatable Fluorescent Imaging Agent
06:46

Non-invasive In Vivo Fluorescence Optical Imaging of Inflammatory MMP Activity Using an Activatable Fluorescent Imaging Agent

Published on: May 8, 2017

Area of Science:

  • Biomedical Optics
  • Nanotechnology
  • Molecular Imaging

Background:

  • Near-infrared (NIR) fluorescence imaging offers significant potential for molecular diagnostics and therapeutics.
  • Its quantitative sensitivity, safety, and ease of use drive its increasing adoption in small-animal research and clinical translation.
  • Deep-tissue fluorescence imaging necessitates effective exogenous NIR-emissive contrast agents.

Purpose of the Study:

  • To review the use of polymersomes for the incorporation and delivery of organic NIR fluorophores (NIRFs).
  • To highlight the potential of this approach for advanced fluorescence imaging applications.

Main Methods:

  • Utilized polymersomes (50 nm to 50 microm) as carriers for NIRFs.
  • Focused on oligo(porphyrin)-based organic NIRFs for their high emissive properties.
  • Reviewed studies involving the incorporation and delivery of these NIRFs via polymersomes.

Main Results:

  • Polymersomes serve as effective vehicles for delivering large quantities of highly emissive organic NIRFs.
  • This strategy facilitates enhanced deep-tissue fluorescence imaging.
  • The approach supports the development of novel contrast agents for diagnostic and therapeutic applications.

Conclusions:

  • Polymersome-encapsulated organic NIRFs represent a promising strategy for advanced in vivo fluorescence imaging.
  • This technology holds potential for noninvasive diagnostics, disease monitoring, and targeted therapies.
  • Further development could accelerate the clinical translation of optical imaging techniques.