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Updated: Jun 17, 2026

07:26
Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
Published on: August 22, 2022
[Diagnostic image. A man with a swelling under his jaw]
Bernard M Tijink1, Remco de Bree
1VU medisch centrum, afd. Keel-, Neus- en Oorheelkunde/Hoofd-halschirurgie, Amsterdam, The Netherlands. bm.tijink@vumc.nl
Nederlands Tijdschrift Voor Geneeskunde
|January 7, 2010
Summary
A 79-year-old man developed a jaw tumor from tuberculosis in a lymph node. This occurred after Bacillus Calmette-Guérin (BCG) treatment for bladder cancer.
Area of Science:
- Oncology
- Infectious Diseases
- Immunology
Background:
- Bladder cancer is a significant health concern.
- Bacillus Calmette-Guérin (BCG) immunotherapy is a standard treatment for non-muscle-invasive bladder cancer.
- BCG treatment can have various side effects and complications.
Observation:
- A 79-year-old male patient presented with a tumor located beneath the jaw.
- The tumor was diagnosed as tuberculosis affecting a lymph node.
- This condition arose subsequent to the patient receiving BCG treatment for bladder carcinoma.
Findings:
- The case highlights a rare presentation of tuberculosis.
- The tuberculosis was localized to a lymph node in the neck region.
- The infection was linked to prior BCG immunotherapy for bladder cancer.
Implications:
- This case underscores the importance of considering opportunistic infections, such as tuberculosis, in patients undergoing BCG therapy.
- It suggests a potential, albeit uncommon, pathway for BCG-related disseminated infection.
- Further vigilance and diagnostic consideration are warranted for unusual presentations in patients treated with BCG for bladder cancer.

