Related Experiment Video
Updated: Jun 17, 2026

Working with Human Tissues for Translational Cancer Research
Published on: November 26, 2015
[Secondary use of human tissue: consent and better information required]
Eric Vermeulen1, Ingrid Geesink, Marjanka K Schmidt
1Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis, Amsterdam, The Netherlands.
Abstract:
Human tissue remaining after diagnostic procedures is important for use in scientific research. This 'secondary use' of tissue is regulated by the Dutch Medical Treatment Contracts Act and the Code of Conduct for Proper Secondary Use of Human Tissue of the Dutch Federation of Biomedical Scientific Societies. Patients have the right to opt-out of further use of their residual tissue, but the procedures for objection and the provision of information involved are not regulated by statute. Dutch patients have a positive attitude to further use of human tissue for other purposes. They prefer, however, a procedure in which they are informed verbally by their health professional about research with residual tissue. The information can be brief and is best provided early in the treatment. Administrative and technical modifications of the current registration systems are necessary to support the opting-out procedure in practice. By taking the preferences of patients into account, trust in medical practice can be maintained.
Related Concept Videos
Nurses' Legal Responsibilities I
The legal responsibilities of a nurse regarding informed consent include the following:
Ethics in Research
Ethical Standards II
Nurses are entrusted with upholding various ethical principles and standards. Nurses forge solid therapeutic relationships using trust, empathy, autonomy, confidentiality, and professional competence.
Confidentiality is crucial, embodying respect for individual privacy and...
Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Bioavailability Study Design: Healthy Subjects Versus Patients
Nursing Ethical Principles II
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's cancer...

