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Related Concept Videos

Cognitive Development During Adolescence01:18

Cognitive Development During Adolescence

During adolescence, individuals experience significant cognitive development that enhances their understanding of others' emotions and thoughts, known as cognitive empathy. This period is marked by an increased ability to adapt to others' perspectives and a more nuanced understanding of others' mental states, a skill that is foundational for social problem-solving and conflict avoidance. The development of cognitive empathy relies heavily on the theory of mind — the recognition that people have...

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Related Experiment Video

Updated: Jun 17, 2026

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

White matter development in adolescence: a DTI study.

M R Asato1, R Terwilliger, J Woo

  • 1Laboratory of Neurocognitive Development, University of Pittsburgh, Pittsburgh, PA, USA. asatomr@upmc.edu

Cerebral Cortex (New York, N.Y. : 1991)
|January 7, 2010
PubMed
Summary
This summary is machine-generated.

Adolescent brain development shows white matter maturation, with females maturing earlier than males. This study reveals key insights into brain connectivity during adolescence and its relation to puberty and sex differences.

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Last Updated: Jun 17, 2026

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
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Published on: July 28, 2013

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DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions
10:05

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Published on: August 26, 2014

Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Radiology

Background:

  • Adolescence involves significant physical and cognitive development, including pubertal changes and sex-based vulnerabilities.
  • White matter integrity changes throughout life, but adolescent-specific maturation, influenced by puberty and sex, remains unclear.

Purpose of the Study:

  • To investigate age-related changes in white matter integrity characterizing adolescence using diffusion tensor imaging (DTI).
  • To explore the contributions of puberty and sex to white matter maturation during adolescence.

Main Methods:

  • Whole-brain DTI scans were performed on 114 participants across childhood, adolescence, and adulthood.
  • Region of interest analyses focused on identifying age-related changes in white matter tracts.

Main Results:

  • Decreasing radial diffusivity was observed across age groups in specific brain regions.
  • White matter maturation supporting cortical and brain stem integration was largely achieved by adolescence.
  • Post-adolescent maturation included prefrontal-striatal and interhemispheric connections, crucial for executive control.
  • Females exhibited earlier white matter maturation compared to males, potentially linked to pubertal timing.

Conclusions:

  • White matter connectivity supporting executive control of behavior is still developing during adolescence.
  • Hormonal influences related to pubertal changes likely impact white matter development.
  • Sex differences in maturation timing highlight distinct developmental trajectories in adolescent brains.