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Updated: Jun 17, 2026

Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets
Published on: March 17, 2023
Design and optimization of a novel surface plasmon resonance biosensor based on Otto configuration
E K Akowuah1, T Gorman, S Haxha
1Broadband and Wireless Communication group, Department of Electronics, University of Kent, Canterbury, CT2 7NT, UK.
Abstract:
A theoretical study on a novel planar waveguide surface Plasmon Biosensor is presented in this paper. The proposed biosensor has a configuration similar to the Otto excitation mechanism for surface Plasmon polaritons. The performance of the device with respect to key system parameters such as gap-width and device length is investigated using an eigenmode solver with perfectly matched layers (PML). Device resolution of 2.3 x 10(-6) RIU has been demonstrated for an aqueous analyte.
