Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Modern Molecular Taxonomy

Modern Molecular Taxonomy

Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...

Molecular Models

Molecular Models

Physical models representing molecular architectures of chemical compounds play essential roles in understanding chemistry. The use of molecular models makes it easier to visualize the structures and shapes of atoms and molecules.

Applications of Molecular Taxonomy

Applications of Molecular Taxonomy

Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...

Predicting Molecular Geometry

Predicting Molecular Geometry

VSEPR Theory for Determination of Electron Pair Geometries

Protein Networks

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...

Molecular Geometry and Dipole Moments

Molecular Geometry and Dipole Moments

The VSEPR theory can be used to determine the electron pair geometries and molecular structures as follows:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Clinical outcomes of regenerative endodontic treatment with injectable platelet-rich fibrin in mature necrotic teeth in a retrospective cohort study.

Scientific reports·2026

Same author

Coping styles for sexual dysfunction and stress among married women of reproductive age: a cross-sectional study from Turkiye.

JPMA. The Journal of the Pakistan Medical Association·2024

Same author

Exploring the impacts of Covid-19 on the electronic product trade of the G-7 countries: A complex network analysis approach and panel data analysis.

PloS one·2023

Same author

First-Principles Investigation of Charged Germagraphene as a Cathode Material for Dual-Carbon Batteries.

ChemSusChem·2022

Same author

Turkish University seniors' knowledge of and opinions on fertility and expectations of having children.

African health sciences·2018

Same author

Efficacy of Diode Laser and Gluma on Post-Preparation Sensitivity: A Randomized Split-Mouth Clinical Study.

Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]·2016

Search research articles

Related Experiment Video

Updated: Jun 17, 2026

Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural Products

Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural Products

Published on: March 12, 2020

Interactive data mining for molecular graphs.

Burcu Yilmaz¹, Mehmet Göktürk

¹Department of Computer Engineering, Gebze Institute of Technology, 10141400 Kocaeli, Turkey. byilmaz@gyte.edu.tr

Journal of Automated Methods & Management in Chemistry

|January 7, 2010

Summary

This summary is machine-generated.

This study introduces a visual molecule mining approach to identify active molecular fragments for drug design. It helps experts discover recurring substructures crucial for developing new medicines.

Related Experiment Videos

Last Updated: Jun 17, 2026

Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural Products

Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural Products

Published on: March 12, 2020

Area of Science:

Medicinal Chemistry
Computational Chemistry
Drug Discovery

Background:

Drug design necessitates analyzing molecular activity to identify key substructures (fragments).
These fragments are vital for understanding molecular structure and designing new therapeutics.
Current methods may lack interactive capabilities for expert-driven fragment discovery.

Purpose of the Study:

To propose an interactive visual molecule mining approach for identifying disease-specific active molecular fragments.
To enable human experts to contribute their knowledge throughout the fragment discovery process.
To facilitate the flexible identification of frequent molecular fragments with exact or varied occurrences.

Main Methods:

A pipelining structure integrating expert input at multiple levels.
Novel combination of histogram-based filtering and clustering techniques.
Interactive visualization of molecular data for expert interpretation.

Main Results:

Successful identification of molecular fragments responsible for specific biological activity.
Demonstrated flexibility in discovering frequent fragments, including those with variations.
Enabled expert-guided discovery through an interactive, visual platform.

Conclusions:

The proposed visual molecule mining approach enhances the identification of active molecular fragments.
This interactive method supports drug discovery by leveraging expert knowledge and advanced computational techniques.
The approach offers a flexible and effective way to find recurring substructures for new drug development.