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Related Concept Videos

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
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Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
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Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
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Related Experiment Video

Updated: Jun 17, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
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Left bundle branch block and changing axis deviation during acute myocardial infarction.

Salvatore Patanè, Filippo Marte, Mauro Sturiale

    International Journal of Cardiology
    |January 8, 2010
    PubMed
    Summary

    This case study highlights a rare instance of left bundle branch block with changing axis deviation during acute myocardial infarction. Such ECG findings are unusual and warrant further investigation in cardiology.

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    Area of Science:

    • Cardiology
    • Electrocardiography

    Background:

    • Changing axis deviation is documented in arrhythmias like atrial fibrillation and acute myocardial infarction.
    • Left bundle branch block typically presents with normal or left axis deviation on ECG.

    Observation:

    • A rare case of left bundle branch block exhibiting changing QRS morphology and axis deviation is presented.
    • This observation occurred in an 86-year-old male patient admitted for acute myocardial infarction.

    Findings:

    • The study details a specific case of left bundle branch block with dynamic axis deviation during acute myocardial infarction.
    • This presentation is atypical and contrasts with the usual ECG findings for left bundle branch block.

    Implications:

    • This case underscores the importance of recognizing rare ECG patterns in acute myocardial infarction.
    • Further research into the mechanisms and clinical significance of changing axis deviation in left bundle branch block is suggested.