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Updated: Jun 17, 2026
07:26
Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model
Published on: July 1, 2018
Staphylococcus intermedius--rare pathogen of acute meningitis.
Peter Durdik1, Marian Fedor, Milos Jesenak
1Department of Pediatrics, Jessenius Faculty of Medicine, Comenius University in Bratislava, Kollarova 2, Martin, Slovak Republic. peter.durdik@gmail.com
Summary
This study details the first reported case of acute meningitis caused by Staphylococcus intermedius in an infant. Successful antibiotic treatment led to a full recovery, highlighting a rare pathogen in pediatric meningitis.
Area of Science:
- Pediatrics
- Infectious Diseases
- Microbiology
Background:
- Acute meningitis is a serious infection of the central nervous system, commonly caused by bacteria like Streptococcus pneumoniae or Neisseria meningitidis.
- Early diagnosis and appropriate antibiotic therapy are crucial for favorable outcomes in pediatric meningitis cases.
Observation:
- An 11-month-old infant presented with clinical signs consistent with acute meningitis.
- Cerebrospinal fluid analysis showed elevated neutrophils and protein levels, indicative of inflammation.
- Microbiological examination identified Staphylococcus intermedius as the causative agent, an uncommon pathogen for meningitis.
Findings:
- The case represents the first documented instance of acute meningitis attributed to Staphylococcus intermedius.
- The infant received cefotaxime, a third-generation cephalosporin antibiotic.
- The patient experienced a complete recovery following the prescribed antibiotic regimen.
Implications:
- This case expands the spectrum of known pathogens causing bacterial meningitis in infants.
- It underscores the importance of comprehensive microbiological investigations to identify atypical causative agents.
- Awareness of Staphylococcus intermedius as a potential meningitis pathogen is crucial for timely and effective treatment in pediatric populations.
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