Related Experiment Video
Updated: Jun 17, 2026

Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model
Published on: July 1, 2018
Staphylococcus intermedius--rare pathogen of acute meningitis
Peter Durdik1, Marian Fedor, Milos Jesenak
1Department of Pediatrics, Jessenius Faculty of Medicine, Comenius University in Bratislava, Kollarova 2, Martin, Slovak Republic. peter.durdik@gmail.com
Abstract:
We report the first case of acute meningitis caused by a rare, atypical pathogen. An 11-month-old infant was admitted to hospital with clinical symptoms typical of acute meningitis. Cerebrospinal fluid analysis revealed an elevated neutrophil cell count and high proteins. Microbiological examination of the fluid confirmed an atypical cause of meningitis--Staphylococcus intermedius. Antibiotic therapy with cefotaxime was successful and the child made a full recovery.
Insights
This study details the first reported case of acute meningitis caused by Staphylococcus intermedius in an infant. Successful antibiotic treatment led to a full recovery, highlighting a rare pathogen in pediatric meningitis.
Area of Science:
- Pediatrics
- Infectious Diseases
- Microbiology
Background:
- Acute meningitis is a serious infection of the central nervous system, commonly caused by bacteria like Streptococcus pneumoniae or Neisseria meningitidis.
- Early diagnosis and appropriate antibiotic therapy are crucial for favorable outcomes in pediatric meningitis cases.
Observation:
- An 11-month-old infant presented with clinical signs consistent with acute meningitis.
- Cerebrospinal fluid analysis showed elevated neutrophils and protein levels, indicative of inflammation.
- Microbiological examination identified Staphylococcus intermedius as the causative agent, an uncommon pathogen for meningitis.
Findings:
- The case represents the first documented instance of acute meningitis attributed to Staphylococcus intermedius.
- The infant received cefotaxime, a third-generation cephalosporin antibiotic.
- The patient experienced a complete recovery following the prescribed antibiotic regimen.
Implications:
- This case expands the spectrum of known pathogens causing bacterial meningitis in infants.
- It underscores the importance of comprehensive microbiological investigations to identify atypical causative agents.
- Awareness of Staphylococcus intermedius as a potential meningitis pathogen is crucial for timely and effective treatment in pediatric populations.
Related Concept Videos
Bacterial Meningitis I: Introduction
Bacterial Meningitis
Bacterial Meningitis II: Pathophysiology
Staphylococcal Skin Infections
Clinical Significance of Antibiotic Resistance
Viral Meningitis
