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Voltammetry: Stripping Methods01:13

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Related Experiment Video

Updated: Jun 17, 2026

Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry
11:37

Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry

Published on: November 29, 2013

Approximate strip exchanging.

Swapnoneel Roy1, Ashok Kumar Thakur

  • 1IBM India Pvt. Ltd., India Software Lab, Information Management, c/ Embassy Golf Links Business Park, Bangalore, India. swapnoneel.roy@in.ibm.com

International Journal of Computational Biology and Drug Design
|January 9, 2010
PubMed
Summary
This summary is machine-generated.

This study introduces strip exchanges as a novel primitive for genome rearrangement. A new 2-approximation algorithm is presented for sorting permutations with minimal strip exchanges.

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Area of Science:

  • Computational Biology
  • Algorithm Design

Background:

  • Genome rearrangements are complex processes modeled by various operations like reversals and transpositions.
  • The strip exchange primitive offers a new perspective on manipulating genomic sequences.

Purpose of the Study:

  • To introduce and analyze the strip exchange primitive for genome rearrangement.
  • To develop an efficient algorithm for sorting permutations using strip exchanges.

Main Methods:

  • The study defines a strip exchange move as an operation that interchanges two chosen strips.
  • A novel 2-approximation algorithm is developed to minimize strip exchanges for permutation sorting.

Main Results:

  • The first non-trivial 2-approximation algorithm for the strip exchange problem is presented.
  • The problem of sorting by strip exchanges is shown to be fixed-parameter-tractable.

Conclusions:

  • Strip exchanges provide a new tool for modeling genome rearrangements.
  • The developed algorithm offers an efficient approach to permutation sorting with practical implications in areas like Optical Character Recognition (OCR).