Related Experiment Video
Updated: Jun 17, 2026

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia
Published on: October 17, 2025
Emerging therapy for the treatment of acute lymphoblastic leukemia
Amber Fullmer1, Susan O'Brien, Hagop Kantarjian
1The University of Texas, MD Anderson Cancer Center, Department of Leukemia, 1515 Holcombe Blvd. Box 428. Houston, TX 77030, USA.
Importance Of The Field:
Over the last few decades, advances in acute lymphoblastic leukemia (ALL) therapy have led to long-term survival rates of > 80% in children; however, comparable rates have yet to be achieved in adults, and a large majority of patients relapse from their disease.
Areas Covered In This Review:
The review describes historical therapy and advancements in ALL treatment over the past few decades, while providing a concise review of the future direction of ALL therapy. Literature was collected through peer reviewed journals and the Pharmaprojects drug profile for ALL.
What The Reader Will Gain:
Current information regarding prognostic factors for relapse, salvage therapy options and emerging drugs are provided in the review.
Take Home Message:
Development of new drugs with novel mechanisms, unique formulations of existing medications, as well as manipulation of current combinations of drugs remain vital to the success in adult ALL.
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