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Calcific panniculitis in adult-onset dermatomyositis
A Abdul-Wahab1, C A Holden, C Harland
1Department of Dermatology, St Helier University Hospital, Carshalton, Surrey, UK. alyawahab@gmail.com
Clinical and Experimental Dermatology
|January 9, 2010
Summary
Dermatomyositis, a rare inflammatory condition, can present with calcific panniculitis. Combination anti-malarial therapy with mepacrine and hydroxychloroquine effectively managed pain and functional loss in two adult cases.
Area of Science:
- Rheumatology
- Dermatology
- Pathology
Background:
- Dermatomyositis (DM) is an idiopathic inflammatory myopathy.
- Characteristic cutaneous manifestations are common in DM.
- Panniculitis is an uncommon finding in dermatomyositis.
Purpose of the Study:
- To describe two cases of adult-onset dermatomyositis with severe calcific panniculitis.
- To evaluate the management of pain and loss of function in these cases.
Main Methods:
- Case report of two adult patients with dermatomyositis.
- Clinical presentation and treatment outcomes were documented.
- Combination anti-malarial therapy was utilized.
Main Results:
- Both patients presented with adult-onset dermatomyositis and severe calcific panniculitis.
- Pain and loss of function were significant clinical issues.
- Combination therapy with mepacrine and hydroxychloroquine showed positive results.
Conclusions:
- Severe calcific panniculitis can complicate dermatomyositis.
- Combination anti-malarial therapy may be an effective treatment strategy for managing associated symptoms.
- Further research is warranted to confirm efficacy.
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