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[Vision jeopardizing xerophthalmia in Denmark].

Sarah Katrine Høngaard1, Jesper Hjortdal

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Summary
This summary is machine-generated.

Severe vitamin A deficiency caused serious eye damage in a Danish alcoholic patient. Prompt treatment with high-dose retinol and cornea transplants improved vision, highlighting the need for nutritional support in vulnerable populations.

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Area of Science:

  • Ophthalmology
  • Nutritional Science
  • Public Health

Background:

  • Vitamin A deficiency is a global health concern, particularly in developing countries.
  • Alcoholism can impair nutrient absorption, increasing the risk of deficiencies.
  • Keratomalacia, a severe eye condition, results from prolonged vitamin A deficiency.

Observation:

  • A 54-year-old male with a history of alcoholism presented with bilateral keratomalacia.
  • Clinical examination revealed corneal ulceration in the right eye and stromal necrosis with perforation in the left eye.
  • Laboratory tests showed critically low serum retinol and beta-carotene levels.

Findings:

  • The patient received high-dose retinol supplementation and corneal transplantation for the left eye.
  • The right eye healed with minimal scarring and a visual acuity of 0.5.
  • The left eye required a second corneal transplant and conjunctival covering, stabilizing vision to hand movements at 1 meter.

Implications:

  • This case demonstrates symptomatic vitamin A deficiency in a socially exposed individual in Denmark.
  • It underscores the importance of nutritional screening and intervention in at-risk populations, including those with alcohol use disorder.
  • Early diagnosis and treatment are crucial to prevent irreversible vision loss from vitamin A deficiency.