Related Experiment Video
Updated: Jun 17, 2026

Preterm EEG: A Multimodal Neurophysiological Protocol
Published on: February 18, 2012
Cortical visual function in preterm infants in the first year
Daniela Ricci1, Laura Cesarini, Francesca Gallini
1Paediatric Neurology Unit, Catholic University, Rome, Italy.
Insights
Most visual functions mature similarly in preterm and term infants during the first year. However, preterm infants show persistent difficulties with fixation shift, indicating potential issues with visual attention and cortical processing.
Area of Science:
- Developmental Pediatrics
- Ophthalmology
- Neuroscience
Background:
- Preterm birth can impact neurodevelopment, including visual pathways.
- Understanding visual maturation in preterm infants is crucial for early intervention.
Purpose of the Study:
- To compare visual function maturation in low-risk preterm infants with term-born infants.
- To identify potential delays or differences in visual development during the first year.
Main Methods:
- Seventy-five low-risk preterm infants (25.0-30.9 weeks gestation) were assessed.
- Ophthalmological examinations and tests for visual fields, acuity, and fixation shift were conducted at 3, 5, and 12 months corrected age.
Main Results:
- Visual function maturation was comparable to term-born infants in most tested areas.
- A significant percentage of preterm infants failed the fixation shift test at all time points (3, 5, and 12 months).
Conclusions:
- Preterm infants exhibit a distinct visual behavior profile.
- Difficulties with fixation shift suggest potential challenges in visual attention and cortical processing in this population.
Objective:
To assess visual function in low-risk preterm infants at 3, 5, and 12 months corrected age to determine whether the maturation of visual function in the first year is similar to that reported in term-born infants.
Study Design:
Seventy-five low-risk infants (25.0-30.9 weeks gestation) underwent ophthalmological examinations and a battery of tests (fix and follow, visual fields, acuity, attention at distance, and fixation shift) designed to assess various aspects of visual function at 3, 5, and 12 months corrected age.
Results:
The results were comparable with normative data from term-born infants in all tests but fixation shift, suggesting that maturation of most aspects of visual function is not significantly affected by preterm birth. In contrast, >25% of preterm infants failed the fixation shift test at 3 months, with a higher percentage of failing at 5 and 12 months.
Conclusions:
There is a specific profile of early visual behavior in low-risk preterm infants, with a high percentage of infants failing a test that specifically assesses visual attention and provides a measure of cortical processing.
Related Concept Videos
Vision
Visual System
Once through the pupil, the light passes through the lens, a...
Motor and Sensory Areas of the Cortex
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.
Anatomy of the Eyeball

